Enrofloxacin
Brands
Baytril
Description
A member of the fluoroquinolone antibiotics, it has a broad spectrum of antibacterial activity that is great against gram-negative bacteria and good against some gram-positive bacteria and Mycoplasma.
Fluoroquinolones work by deactivating bacterial enzymes necessary for the transcription of DNA. DNA is very tightly coiled in order to fit inside a cell. Segments to be used must be uncoiled by an enzyme called DNA gyrase. The fluoroquinolone antibiotic deactivates DNA gyrase making the reading of DNA impossible. The bacterial cell dies.
Uses
- Mycoplasma
- Staphylococci
- Urinary tract infections
- Soft tissue injury
Dosage
- 10 mg/kg orally, twice daily (24)
- 100 mg/litre in drinking water (24)
- 5 mg/lb orally, twice daily (7)
- 0.2 ml/lb orally for 14 to 30 days (7)
- 2.5-5.0 mg/kg orally or by injections, twice daily (20)
Side Effects
- Seizures
- Diarrhoea
- Itching, redness, soreness at injection site
Combinations
Incompatibilities
Theophylline
