Tylan; Elanco


It is similar in structure, mechanism of action, and spectrum as that of Erythromycin, but more active against certain Mycoplasma.


  • Mild and chronic symptoms of respiratory disease caused by Mycoplasma, however does not always show any effect
  • Skin/soft tissue infections caused by some Streptococci


  • 4.5mg/lb BID, PO, SQ or IM for 14 to 30 days (7)
  • Tylan Soluble Powder - 1/8 teaspoon in 8 oz water, fresh every 3 days for 14 to 30 days (7)
  • 0.5 mg/kg in drinking water (20)
  • 10 mg/kg orally or by injection twice a day (20)

Side Effects

  • Diarrhoea
  • Liver damage
  • Itching


  • Remove moist food from diet to try to encourage the rat to drink.
  • An injectable form is available, but pain and swelling occur at the injection site
  • Frequently has no effect on symptoms


Chloramphenicol Palmitate, Chloramphenicol Sodium Succinate, macrolides (Azithromycin, Clarithromycin, Erythromycin) - chloramphenicol has mechanisms similar to the macrolides; they may be prevented from binding, or prevent a macrolide from binding to the subunits of bacterial ribosomes.