Chloromycetin Sodium Succinate


A broad-spectrum systemic antibiotic that affects a wide range of bacteria, and penetrates tissues other antibiotics cannot (e.g., central nervous system and eyes). It works by interfering with the protein synthesis inside invading bacteria, preventing their reproduction. Very expensive, and only available via prescription.


  • Clostridium
  • Mycoplasma
  • Salmonella
  • Staphylococcus
  • Streptococcus


  • 25-90 mg/lb orally, three times daily (7)
  • 30-50 mg/kg, by injection, twice a day (20)

Side Effects

  • Anaemia
  • Diarrhoea
  • Anaphylaxis
  • Bone marrow suppression


  • Do not give to pregnant/lactating rats
  • Chloramphenicol on its own is a very toxic substance, which inhibits the growth and production of red blood cells in the bone marrow
  • Do not give salicylates (any of a group of analgesics, or painkilling drugs, that are derivatives of salicylic acid) or non-steroidal anti-inflammatory drugs while administering this drug


Azithromycin, Erythromycin, Tylosin