Trimethoprim Sulfa
Types
Trimethoprim Sulfadiazine; Trimethoprim Sulfamethoxazole
Brands
Bactrim; Septra; Sulfatrim; Cotrim (Trimethoprim Sulfadiazine)
Tribrissen (Trimethoprim Sulfamethoxazole)
Description
An broad-spectrum anti-bacterial substance, used against a variety of bacterial organisms.
It is a combination of two active ingredients. Both affect a vitamin called folic acid and its activity in bacteria causing destruction of its metabolic function in the bacteria.
Uses
- Certain urinary tract infections
- Skin infections
- Any secondary infections - bronchitis, pneumonia, Streptococci and some strains of Staphylococcus
- Not effective against Mycoplasma
Dosage
Side Effects
- Diarrhoea
- Rash and/or itching
- Anaphylaxis (exaggerated allergic reaction on second dose if this state develops)
- Joint inflammation
Warnings
- Keep rat well hydrated
- Birth defects have been reported after this medication was given to pregnant rats (21)